Hypothyroidism, also known as ‘underactive thyroid’ is one of the common manifestations of thyroid hormone deficiency in the body. With a global prevalence rate ranging from 0.25% to 4.20%, the risk factors of hypothyroidism include sex, lack of certain nutrients, use of certain drugs as well as underlying comorbid conditions. The present article provides a brief overview of hypothyroidism and discusses the risk factors, epidemiology, and etiology of this condition. Disease Overview Hypothyroidism is the condition that occurs due to the inadequate synthesis of thyroid hormone in the body.

Iodine deficiency is also responsible for hypothyroidism. Hypothyroidism is of two types: primary and secondary. Primary hypothyroidism occurs due to disorder in the thyroid gland, accounting to 95% of cases of hypothyroidism. On the other hand, secondary hypothyroidism occurs due to disorder of the…