A 54-year old woman was presented to a dental clinic with a 1-year history of oral swelling and sore mouth. She regularly chewed loose-leaf tobacco for up to five times a day for more than 10 years. She mentioned that she always placed the tobacco on the floor of her mouth between the jaw and tongue. Examination Intraoral examination revealed an irregular, indurated lesion of 3cm in its greatest dimension and was located on the floor of the mouth (panel A). Incisional biopsy was performed (panel B).
CT and PET imaging showed no bony or lymph node involvement. From the clinical and pathological indications, do you think it is a mouth carcinoma? *This case is from Docplexus editorial team for educative purpose only. Source: NEJM Stay Connected, the answer will be posted in the next 48h!
