As per Meyerding classification, high-grade spondylolisthesis (HGS) is the slippage of more than 50% of a vertebral body relative to an adjacent one and is the most common in the lumbosacral region or at the L5-S1 level. It usually requires a surgical treatment but a few points to be considered for surgery include: The procedure should prevent further anterior displacement of the vertebral body Prevent neurological damage while reducing the translation Prevent implant failure, especially when the anterior spinal column is not involved This question is from the Editorial team of Docplexus and is meant for educational purposes only. Reference: Delgado-Fernández, J., Frade-Porto, N., Blasco, G., González-Tarno, P., Gil-Simoes, R., Rivas, P. P., & de Sola, R.

G. (2021). Long term outcome and fusion rate of transdiscal fixation for L5-S1 high grade spondylolisthesis. Clinical Neurology and…