Metastasis of malignant neoplasms to bone is common with metastasis being far more prevalent than primary bone malignancies. Bone is the third most common organ affected by metastasis, surpassed only by the lungs and liver. An early detection of skeletal metastasis is critical for accurate staging and optimal treatment. This article describes the available imaging methods to diagnose bone metastasis.
Advances in the understanding of tumor biology have led to the development of improved treatment strategies for many cancers. With an increased prevalence of bone metastasis, there is potential for significant comorbidities such as pain, limited mobility, hypercalcemia, spinal cord or nerve root compression, myelosuppression and pathologic fracture too. As a result, an early detection of skeletal metastasis is critical for accurate staging. Pathophysiology Metastasis of bone can occur…
