A new study of influenza infection in an animal model broadens the understanding of how the immune system responds to flu virus, showing that the process is more dynamic than usually described engaging a broader array of biological pathways. The researchers say their findings may offer key insights for designing more effective vaccines in general. "During infection, viral proteins are present into the entire cell, not just in the limited compartments that have been the focus of attention in classical immunology," said study leader Laurence C.
Eisenlohr, Ph.D., a viral immunologist in the Department of Pathology and Laboratory Medicine at The Children's Hospital of Philadelphia (CHOP). "By investigating how active infections interact with mechanisms deep inside immune cells, we can design vaccines with broader protection against invading pathogens." A detail study can be done regarding…
