Nasal carriage of Staphylococcus aureus represents a well-defined factor of risk involving the community and hospital-acquired infections. Recently a significance of immune determinants in nasal S. aureus colonization has been identified. This article outlines the clinical findings of a study that investigated the frequency of nasal S. aureus carriage in patients with persistent allergic rhinitis and its possible influence on their symptoms and immune markers.
Nasal carriage in S. aureus colonization frequently occurs in patients with perennial allergic rhinitis (PAR). It exerts an immunomodulatory effect in patients with atopic dermatitis and it may contribute to airway inflammation and allergic response in patients with allergic rhinitis. According to recent clinical findings, S. aureus can harbor antigens which exert immunomodulatory and proinflammatory effects via activation of…