Inflammation plays a crucial role in the development of heart failure (HF). Similarly, infections are linked to dysregulation of immune response and worsening HF symptoms. To explore this connection, a study has examined whether infection-related hospitalization (IRH) influences the risk of HF in 14,468 adults aged 45 to 64 years.
A 27-year follow-up study found that IRH was associated with an increased risk of HF events among participants compared to the control group (hazard ratio [HR]: 2.35) This association remained consistent across various types of infections, including respiratory, urinary tract, blood/circulatory, digestive tract, skin, and hospital-acquired infections. Notably, IRH was linked to both HF with ejection fraction (HR: 1.77) and HF with preserved fraction (HR: 2.97). These findings suggest that IRH may contribute to HF development and serve as a modifiable risk…
