Improving informed consent to participate in randomized clinical trials (RCTs) is a key challenge in cancer communication. The current article reports a study which examined strategies for enhancing randomization comprehension among patients with diverse levels of health literacy and identifies cognitive and affective predictors of intentions to participate in cancer RCTs. Randomized clinical trials (RCTs) remain the gold standard in developing medical treatments for cancer and are essential for translating biomedical discoveries into evidence-based patient care.
A key barrier to patient participation in RCTs is how randomization to treatment condition is explained during the informed consent process. Randomization is a highly technical term for which there are no lay language synonyms; thus healthcare providers often struggle to adequately translate this concept for patients,…
