Both type 1 and type 2 diabetes have been associated with reduced pulmonary function , but the underlying metabolic mechanisms remain unclear. To investigate this relationship, researchers analyzed data from the German Diabetes Study , evaluating spirometry measurements in individuals with type 1 diabetes, type 2 diabetes, and participants with normal glucose tolerance. The analysis included 426 participants with type 1 diabetes, 482 with type 2 diabetes, and 244 controls.
Higher insulin sensitivity and greater insulin clearance were significantly associated with better lung function, reflected by higher forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). In contrast, individuals with type 2 diabetes demonstrated lower FEV1 and FVC compared with those with type 1 diabetes and controls. Among participants with type 1 diabetes, higher daily insulin doses were…
