Complex coronary artery lesions are associated with increased procedural challenges and adverse cardiovascular outcomes, yet long-term evidence comparing intravascular imaging-guided percutaneous coronary intervention (PCI) with conventional angiography-guided PCI remains limited. To address this gap, a study evaluated the long-term clinical outcomes of intravascular imaging-guided PCI versus angiography-guided PCI in patients undergoing intervention for complex coronary artery lesions in 1,639 patients.
Over a median follow-up of 5.3 years, the study found that the primary endpoint occurred significantly less frequently in the intravascular imaging-guided PCI group compared with the angiography-guided PCI group (10.5% vs 14.9%; HR: 0.68). Cardiac death or target vessel-related myocardial infarction was also lower with intravascular imaging-guided PCI (7.6% vs 10.7%), along with…
