According to the recent study published in Pain Medicine, researchers claimed that intravenous (IV) lidocaine provides similar analgesia for undifferentiated severe pain when compared with IV morphine. A pilot, unblinded, randomized controlled trial which aimed to compare the analgesic effects of IV lidocaine and IV morphine for the treatment of severe pain in emergency department reported similar pain relief and satisfaction in both study groups. Moreover, study suggests that lidocaine group participants showed fewer side effects and needed less morphine.
The study involved 32 patients aged >18 years with severe pain. Then, participants were randomized to administer IV lidocaine such as 75 mg if body weight is <50kg, 100 mg if 50-100 kg and 150 mg if body weight is >100 kg for 10 minutes, followed by a 50-minute IV lidocaine infusion of same dose or provider selected dose of morphine.…
