Psoriasis is a chronic relapsing autoimmune skin disease which affects not only adults but also pediatric population. About 2-4% of the total population is affected by Psoriasis. Genetic predisposition and environmental factors are considered to activate the disease. During psoriasis, there has been increased risk of other autoimmune disorders such as ulcerative colitis, Crohn’s disease, and autoimmune thyroiditis.
Psoriasis which is a common autoimmune disease of the skin usually presents with itchy red, scaly patches, papules and plaques of different severity. Various neuropeptides including Hypothalamic-Pituitary-Adrenal (HPA), Hypothalamic-Pituitary-Thyroid (HPT) and a source of vitamin D are often synthesized on the skin, as its the site of synthesis and metabolism. As various thyroid hormone receptors are expressed in human skin which exerts effects on epidermal proliferation and…
