The traditional histopathological assessment of surgically resected tissue is a time consuming and cost-ineffective process. Now, researchers have developed a new microscope that can scan a 3D tissue sample cut out during surgery and quickly get the results. Limitations of traditional histopathological evaluation: The traditional procedure involves fixation, dehydration, embedding, sectioning, staining of the tissue sample before microscopic evaluation thus making the procedure: Expensive Time-consuming Destructive Hazardous Although there is some modification such as frozen sectioning instead of paraffin embed tissue may reduce the time, such new procedure may not give reliable data in several tissues.

Another problem is that the currently practiced histopathological procedures only scan a small fraction of 2-D sections out of a large 3-D sample. This leads to less than 1% of the…