Thyroid function test has become one of the most common test to be performed apart from routine tests. Excluding infertility, none of the other conditions warrants Thyroxine treatment for subclinical hypothyroidism. Subclinical hypothyroidism is defined biochemically as an elevated serum thyroid-stimulating hormone (TSH) and a normal serum free thyroxine (T4) level.
Some patients with subclinical hypothyroidism may have vague, nonspecific symptoms. Although virtually all experts recommend treatment of subclinical hypothyroidism when serum TSH concentrations are ≥10 mU/L, treatment of patients with TSH values between the upper reference limit and 9.9 mU/L remains controversial, particularly in older patients who are more likely to have complications from unintended overtreatment. In a randomized trial evaluating the effect of Levothyroxine versus placebo on quality of life measures in…
