Acute allergic reactions can take on a range of different clinical presentations and involve numerous organs. Although there are no universal criteria for diagnosis, it’s often necessary to critically assess the cardinal signs-symptoms and patient’s vulnerability to a potential allergen, the to begin an effective treatment. This article outlines the strategies and pharmacological compounds that are necessary to intervene acute allergic symptoms. The acute allergic reaction is a condition characterized by a number of symptoms ranging from localized rash to rapidly progressing potentially fatal anaphylaxis.
Basophil and Mast cell degranulation results in the release of inflammatory mediators like prostaglandins, tryptase, cytokines, histamine, chemokine etc. that causes, vasodilation, smooth muscle contractions & increased vascular permeability etc. The cardinal signs are erythema, edema,…
