Synopsis Sickle cell disease (SCD) is categorized in an autosomal recessive inherited disorder of red blood cells that affects hemoglobin, the molecules that carry oxygen to cells throughout the body. This disorder is caused due to mutation in gene HBB in which a typical hemoglobin S distort RBCs into sickle, or crescent, shape. SCD is a lifelong illness and therefore may also cause to suffer from chronic conditions. Sickle cell disease is a genetic disorder and is significantly observed in populations from Sub-Saharan Africa, South America, Caribbean, Central America, Saudi Arabia, India, and Mediterranean countries.
This Week’s “MEDFACT” discusses an Interventional, Randomized control trial from the Journal ‘’The New England Journal of Medicine’’ , A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease. Authors: Elliott Vichinsky, M.D., Carolyn C. Hoppe, M.D., Kenneth I.…
