Coronary artery disease (CAD) is a complex disease that causes reduced or absent blood flow in arteries that encircle and supply the heart. The diagnosis and subsequent treatment of CAD represents a major challenge to healthcare systems worldwide, affecting millions of patients each year. Despite the prevalence of evidence-based data, the optimal approach for the evaluation of CAD, especially the stable CAD remains unclear.
Stable Coronary Artery Disease (SCAD) SCAD is characterized by episodes of transient angina pectoris, often triggered by exercise, emotion or other forms of stress, generally triggered by a reversible mismatch between myocardial oxygen demand and supply resulting in myocardial ischemia or hypoxia. Pathophysiology Myocardial ischemia and hypoxia in SCAD are caused by a transient imbalance between blood supply and metabolic demand. The consequences of ischemia occur in…
