Synopsis Pharmacotherapies seems to be effective in quitting smoking but concerns have been raised regarding the cardiovascular safety of such medications. In this trial, the safety of varenicline, bupropion, and nicotine replacement therapy was tested and it was found that these medications do not increase the risk of serious cardiovascular events. This week’s ‘ MED FACT ’ discusses a clinical trial from JAMA Internal Medicine , “Cardiovascular Safety of Varenicline, Bupropion, and Nicotine Patch in Smokers: A Randomized Clinical Trial. 2018”.

Authors : Benowitz NL, Pipe A, West R, Hays JT, Tonstad S, McRae T, Lawrence D, St Aubin L, Anthenelli RM. Key Takeaways In a general population of smokers, smoking cessation medications do not increase the risk of serious cardiovascular events. Objective: To compare the relative cardiovascular safety risk of smoking cessation treatments Study…