Pain in migraine is related to the higher salivary levels of nitrate-, nitrite- and nitric oxide (NO)- reducing bacteria, according to the research published in a renowned journal from American Society For Microbiology. Pathophysiology Nitrate-containing compounds have been identified as common headache triggers. Food preservatives are frequently identified triggers for those who suffer from migraines. Also, cardiac medications containing nitrates may cause severe headaches, which occur in over 80% of patients taking them.
10% of patients cannot tolerate nitrate therapies due to unbearable headaches. Nitrate-induced headaches typically manifest in one of two ways: Immediate headaches with mild to medium severity developing within an hour of medication ingestion Delayed headaches occurring 3 to 6 h after nitrate intake that are much more severe, with migraine-like symptoms. Delayed…
