The iatrogenic adverse effect in medical treatment can complicate the patient outcome. Drug interactions inside the body often lead to undue disadvantages. Although gastroenteritis is a common problem among the populations with a range of etiologies, several classes of drugs have strong involvement as well. NSAIDs are known to be involved with a gastroduodenal mucosal injury. Prolong use of NSAIDs leads to inhibition of prostaglandin synthesis that have an adverse effect on the mucosal lining of the gut.
NSAIDs are also induced direct acidic damage. This problem is widespread because of the rampant use of such class of drugs and availability as OTC medicine. Several other drugs are also involved in the ulcer of the esophageal tract. These includes aspirin, tetracycline, quinidine etc. Many drugs such as cisplatin, cyclophosphamide etc have a significant emetogenic effect since they have…
