A post hoc analysis of an international, multicenter randomized trial evaluated the durability of surgical mitral valve (MV) repair in 314 patients (median age 67.4 years; 24.2% women) with degenerative mitral regurgitation (DMR) and concomitant moderate or less tricuspid regurgitation. The analysis included patients from 39 sites after excluding 87 of the 401 randomized participants who underwent MV replacement, had non-isolated DMR, or lacked evaluable echocardiographic follow-up. Echocardiographic outcomes were independently adjudicated by a core laboratory.
The primary endpoint was treatment failure, defined as all-cause mortality, recurrent severe MR, or MV reoperation within 2 years. At discharge, moderate and severe MR were present in only 1.0% and 0.7% of patients, respectively, while 30-day mortality was 1.0%. At 2 years, all-cause mortality was 3.5%, MV reoperation occurred in…
