A healthy 15-year-old girl was presented to the pediatric clinic with slight mucosal thickening and swelling in the right hard palate below teeth #s 4 & 5. The swelling was asymptomatic and of unknown duration. It was the same color as the surrounding mucosa and was firm to palpation. It was smooth-surfaced with defined borders around 2 X 1.5 in length and width. A small Incisional biopsy was performed. Past Medical History Her medical history is not significant for any diseases or allergies.
Biopsy The histologic evaluation of the Incisional biopsy revealed a small fragment of oral mucosa with an underlying mass of mesenchymal origin. This mass was made up clusters, cords and sheets of large cells with granular cytoplasm and small oval to round nuclei. These cells were positive with S-100 protein marker indicating the neural crest origin. There was no evidence of atypia. The…