A study at the University of Colorado turns out a linkup between bacteriophages and inflammatory bowel disease. The bacteriophages invade the intestinal mucosa and rise abundantly in bowel causing ulcerative colitis as well as Crohn’s disease. The researchers said, the role of these bacteriophages in the pathogenesis of IBD is still unidentified. A good balance of microbes in the gut is difficult to maintain.
Changes in the composition of gut flora may cause an inflammatory response. Significant health burden of IBD led to the investigation of environmental factors causing recurrent inflammation of the bowel. "We hypothesize that inflammatory host defenses alter bacteriophage abundances during colitis and we can use bacteriophages as markers to diagnose the IBD ", the researchers said. Source: The Economic Times In your opinion, which factors should be considered while detecting IBD?
