Several studies have demonstrated that individuals with type 2 diabetes (T2D) have a significantly lower urinary iodine concentration (UIC) and a higher risk of frailty compared to healthy individuals. Additionally, low UIC is associated with an increased risk of hypertension , dyslipidemia, and coronary artery disease. To explore these associations further, a study has examined the effects of non-iodized salt consumption and lower UIC on frailty risk in 850 T2D patients, with a median age of 65.6 years.

The study found that consuming non-iodized salt ย (relative risk [RR]: 1.09) and having lower UIC (RR: 1.10) increase the risk of frailty in T2D patients compared to those who consumed iodized salt. Notably, this risk was particularly linked to high serum thyroid-stimulating hormone levels (RR: 1.20) and low free thyroxine levels (RR: 1.15) in patients who consumed non-iodized salt. โ€ฆ