There is marked variability in the degree of pain relief by NSAIDs due to the complex interplay of molecular mechanism contributing to the pain sensation, variability in the disposition of NSAIDs and imprecision in the quantification of human pain. This article discusses the side effects of using NSAIDs on kidney. An analgesic is a medicine intended to relieve pain. Over-the-counter analgesics include aspirin, acetaminophen, ibuprofen, naproxen sodium, and others. These drugs present no danger for most people when taken in the recommended dosage.

But some conditions make taking even these common painkillers dangerous for the kidneys. Also, taking one of these drugs regularly over an extended period may increase the risk for kidney problems. Most drugs that can cause kidney damage are excreted only through the kidneys. That is, they are not broken down by the liver, as alcohol is, or…