Pain in children is often underdiagnosed, misunderstood and undertreated. It is evident that even neonates show a physiologic response to painful stimuli. Moreover, recent findings have shown that children often do not receive the same treatment as adults with similar painful conditions. This article overviews periprocedural safety that should be considered during pediatric sedation.

It is imperative to discuss the risks, benefits, and alternatives with the parent or guardian before initiation of procedural sedation. In addition, the written consent should be taken as determined by an institutional, local, or state mandate to avoid any medico-legal issues. Safety considerations According to several guidelines, children of all ages should be nil per os (NPO) for clear liquids 2 hours before undergoing sedation. Moreover, recommendations suggest that the duration of NPO for solid food and…