Compared to normothermia, hypothermia has been shown to reduce death or disability in neonatal hypoxic-ischemic encephalopathy. However, more research is needed to establish any relation between rewarming therapy and associated abnormality. Hypoxic-ischemic encephalopathy is a clear clinical syndrome in newborns due to fetal asphyxia at birth. Its incidence rate is around 25 out of every 1000 newborns in developing countries.
The causes include detachment of the placenta, prolapse of the umbilical cord, and uterine rupture. Newborns with this syndrome are incapable of crying, breathing at birth, even when stimulated and require assisted ventilation in the delivery room. The clinical forms are mild to moderate, of which the moderate and severe forms are known to cause permanent neurological deficits and neurodevelopmental defects. A recent study was conducted with the following…
