Hypoglossal nerve stimulation (HGNS) is a treatment for obstructive sleep apnea (OSA) in patients who cannot tolerate positive airway pressure therapy, yet evidence for its effectiveness in this population remains limited. To address this gap, a study evaluated the efficacy and safety of proximal HGNS (pHGNS) in 104 patients with OSA. The study found that 58.2% of patients receiving proximal hypoglossal nerve stimulation (pHGNS) achieved the primary end point compared with 13.5% in the control group, and oxygen desaturation index (ODI) was reduced by at least 25% in 68.7% versus 37.8% of patients, respectively.
Median Epworth Sleepiness Scale scores improved from 10.0 at baseline to 6.0 at month 7 in the treatment group, while remaining unchanged in the control group (9.0 to 9.0). No serious procedure-related adverse events were reported. These findings suggest that pHGNS improves…
