In this ESC CardioPractice podcast, Dr. Konstantinos Koskinas from Bern University Hospital joins Dr. Dimitris Richter to unpack the 2025 Focused Update to the ESC/EAS Dyslipidaemia Guidelines, incorporating evidence up to March 2025. Key novelties include SCORE2/SCORE2-OP risk calculators , Lp(a) as a critical risk modifier prompting intensified therapy, high-intensity statin plus ezetimibe combo from ACS index hospitalization, and bempedoic acid for statin-intolerant patients.

The update stresses combination therapies to hit aggressive LDL-C targets (e.g., <40 mg/dL in extreme risk), early post-ACS lipid intensification , and tailored approaches for HIV or cancer patients. Dive into the 2025 ESC dyslipidaemia revolution with experts guiding bolder lipid strategies for your high-risk patients. To access the podcast: Click here ##Reference## Koskinas K, Richter D. The updated 2025 ESC…