Dentin hypersensitivity , although prevalent, has no permanent solution. The existing treatments are short-lived. However, a study has demonstrated a durable biomimetic restoration of demineralized dentin from extracted teeth. The process promotes the occlusion of exposed dentin tubules with peritubular mineralization.
The process uses amelogenin-derived peptide to guide the layer-by-layer remineralization, forming an infiltrating, integrated mineral layer on dentin. Additionally, peritubular mineralization creates a robust and durable interface or biomimetic mineral-dentin junction between the interpenetrating mineral layer and underlying dentin. This interface mimics biological dentin-enamel junction and can withstand long-term mechanical and thermal stresses, common in oral environment. This peptide-guided remineralization procedure has improved the prospects of a much-needed…
