With 63,990 new cases in 2017, Renal Cell Carcinoma (RCC) is comprised of 2-3% of all cancer incidents. In India, RCC demonstrates early onset and late-stage presentation. Characterized by 3 classical symptoms of hematuria, flank pain, and abdominal mass, the tumor often leads to poor prognosis. European Association of Urology revealed practice guidelines for urologists, nephrologists, and oncologists on how to deal with the diagnosis and management of RCC.
DIAGNOSIS: The guideline starts with the classical triad of clinical presentation of RCC. This also provides a list of most common (30% cases) paraneoplastic syndromes associated with cancer. This includes: Cachexia Amyloidosis Neuromyopathy Hypercalcemia Polycythemia and others Diagnosis is significantly dependent on Physical examination, imaging, and laboratory findings . Physical examination is characterized by palpable abdominal…