We have a  syndrome already discussed keratoconus in detail that it is a degenerative disorder characterized by non-inflammatory corneal ectasia. It is not a visual threatening condition but a visual disturbing  some of the rare association with this disorder are as follows   Ectopia lenses Osteogenesis imperfecta Blue sclera KCS Retinitis pigmentosa Vernal kc Severe rubbing of eyes Downs Turners Ed syndrome Leber's amaurosis Marfans Mitral valve prolapse syndrome Severe mental retardation Achondroplasia Share your views.