A 32-year-old woman was referred to an obstetrician for advice regarding her pregnancy. She had a medical history of three spontaneous miscarriages in the first trimester. There was no history of infections in these pregnancies. The fetus had not been examined, but there was no family history of genetic disease or recurrent fetal loss. She had been extremely well, but she and her husband were anxious.
She had no obvious rash, arthritis, or bruising and appeared to have a normal uterus and cervix. Blood tests were negative for cardiolipin and high-titer IgG antineutrophil antibodies, and C-reactive protein measurement was normal. What is your most probable diagnosis for this patient? (The answer will be posted soon!) Source : Essentials of Clinical Immunology *This Case Challenge is from the Editorial Team of Docplexus and is meant for educational purposes only. ##Disclaimer## The…