A 33-year-old obese man with a history of recurrent skin abscesses due to methicillin-resistant Staphylococcus aureus (MRSA) presents to the emergency department with a productive cough, pleuritic chest pain, and dyspnea. One week ago he had influenza. Chest radiography shows multilobar infiltrates and early cavitation. A sputum Gram stain shows numerous gram-positive cocci in clusters.
The sputum culture grows 3+ S aureus, which has a MIC of less than 2 to oxacillin, 2 to vancomycin, and greater than 4 to clindamycin and which are susceptible to daptomycin, linezolid, and quinupristin/dalfopristin. Which antimicrobial regimens would you suggest for treating the patient's infection? *This case is from Docplexus editorial team for educative purpose only
