Pharmacogenomics is the study of how an individual’s genome affects his/her response to a specific drug or treatment. This relatively new concept in precision medicine helps correlate the gene expression pattern with a drug’s efficacy and toxicity. Pharmacogenomics has been applied extensively to treat several diseases by customizing therapies that improve efficacy and have minimal side-effects. Pharmacogenomics plays an important role in cancer screening and treatment.
1 Most cancers arise due to over-expression of genes or mutations in gene regulation, which leads to abnormal cell growth. Therefore, a study of genetic polymorphisms aids in predicting the risk of developing cancer and the prognosis of the anticancer treatment. Pharmacogenomic markers in oncology Pharmacogenomic markers 1,2 correlate the germ-line genetic variations or somatic variations in the cancer cells with the…
