The clinical value of routine terminal ileal intubation (TII) during colonoscopy in asymptomatic individuals undergoing colorectal cancer (CRC) screening or post-polypectomy surveillance remains uncertain. To clarify its diagnostic utility, researchers conducted a systematic review and meta-analysis of 11 studies involving 25,659 patients, of whom 13,672 underwent TII during colonoscopy. The pooled analysis showed that the overall diagnostic yield for any ileal finding was 1.74% . However, most abnormalities detected were non-specific and did not require clinical intervention.
Importantly, the diagnostic yield for clinically significant pathology was markedly lower at 0.28% . Additionally, the detection rate for Crohn’s disease was only 0.1%, corresponding to approximately one case per 1,000 ileoscopies performed during screening colonoscopy. These findings indicate that routine TII in…