A prospective cohort study published in The Journal of Nutrition, Health and Aging evaluated the association of sarcopenia with lung function and the risk of developing respiratory diseases, along with the potential contribution of inflammatory and metabolic pathways. The study analyzed data from 317,628 adults enrolled in the UK Biobank over a median follow-up of 14 years.
Researchers found that both probable and confirmed/severe sarcopenia were consistently associated with poorer lung function and increased risk of incident respiratory disease. Compared with individuals without sarcopenia, participants with probable sarcopenia showed a significantly higher risk of overall respiratory disease (HR: 1.30; 95% CI: 1.26–1.36), chronic obstructive pulmonary disease (HR: 1.37; 95% CI: 1.24–1.50), asthma (HR: 1.35; 95% CI: 1.23–1.48), and interstitial lung disease (HR: 1.74; 95% CI:…
