A study held at national university heart center(NUHC), Singapore discovered a substantial means to trigger self-healing of damaged heart cells. For the first time, researchers have identified a long noncoding ribonucleic acid (ncRNA) that regulates genes controlling the ability of heart cells to undergo repair or regeneration. In this study, the researchers used single cell technology to explore gene expression patterns in healthy and diseased hearts. They further discovered that a unique subpopulation of heart cells in diseased hearts activate gene programs related to heart cell division, uncovering the gene expression heterogeneity of diseased heart cells.
Moreover, they found the “brakes” that prevent heart cells from dividing and self-healing. Targeting these “brakes” could help trigger the repair and regeneration of heart cells. Source: Kelvin See et al., Single cardiomyocyte…
