Sjögren syndrome is characterized by autoimmune inflammation and destruction of lacrimal and salivary glands. The condition is classified as primary when it exists in isolation, and secondary when associated with other diseases such as rheumatoid arthritis, SLE, systemic sclerosis, mixed connective tissue disease, primary biliary cirrhosis, chronic active hepatitis and myasthenia gravis. Primary Sjögren syndrome affects females more commonly than males and is characterized by the following: Presentation is in adult life with grittiness of the eyes and dryness of the mouth Enlargement of salivary glands and occasionally lacrimal glands, with secondary diminished salivary flow rate and a dry fissured tongue. Dry nasal passages, diminished vaginal secretions and resultant dyspareunia.
Raynaud phenomenon and cutaneous vasculitis. Arthralgia, myalgia and fatigue may be present. Complications…
