A 51-year-old man is referred for an urgent opinion with an 8-week history of intermittent swellings affecting his hands, feet, face and genitalia. He also describes intermittent abdominal bloating and pain. Over the last three weeks, he had attended the accident and emergency department on two occasions. The first time, when he presented with lip and tongue swelling but without shortness of breath. He was treated with antihistamines and intravenous hydrocortisone but did not require adrenaline or intubation.
On the second occasion, with acute and severe abdominal pain associated with vomiting and was admitted within 24 hours under the surgical team for investigation of an acute abdomen pain. He does not describe any associated urticaria but does complain of recent-onset night sweats, weight loss, and low energy levels. What could be the probable diagnosis? *This case is from Docplexus…