Approximately 50% testicular germ cell tumors (TGCT) are pure seminomas and 50% are non-seminomas. The vast majority of GCT arise in the testicles with ∼5% occurring outside of the gonads, i.e. extragonadal germ cell tumor (EGGCT). EGGCTs are usually found in the body’s mid-line, e.g. retroperitoneum, mediastinum or cerebrum, sometimes posing diagnostic difficulties.
This article is a brief synopsis of the clinical practice guideline attached here that includes details on diagnosis, treatment and follow-up of testicular seminoma and non-seminoma. Diagnosis In patients with a testicular mass, testicular sonography (7.5 MHz transducer) should be carried out, also noting the size and any structural alterations of the contralateral testis. Diagnosis of a testicular germ cell cancer (TGCC) is based on histology of the testicular mass. Elevation of ‘ tumor markers’ , i.e. serum levels of…
