Thalassemia is a form of hemolytic anemia. It is an autosomal recessive disorder . If two individuals with 'thalassemia minor trait' marry, the chance of the offspring having thalassemia major is 25%. Hence screening is necessary in our community. What is thalassemia? Thalassemia is a genetic disorder where there is abnormal hemoglobin production. This inherited disability of hemoglobin production, with a partial or complete failure to synthesize a specific type of globin chain, leads to a condition known as hemolytic anemia, in which RBC breakdown occurs.
Mild jaundice can also occur. What Are the Types of Thalassemia? There are two types of thalassemia: It can be, Alpha thalassemia or Beta-thalassemia. Or it can be Thalassemia minor or Thalassemia major. 1. Alpha and Beta-Thalassemia: Alpha Thalassemia- In alpha thalassemia, deletion of one or both genes on the short arm of chromosome…
