The MAL antigen, discovered as part of the new MAL blood group system, is the AnWj antigen. This antigen was previously identified in 1972 but its genetic basis was unknown until the recent discovery of the MAL system. The AnWj antigen is a surface marker on red blood cells, and individuals lacking this antigen can have transfusion reactions if they receive AnWj-positive blood, according to a news article from the University of Bristol.
Some points worth noting about it: The discovery of the MAL system provides the genetic foundation for the AnWj antigen The AnWj antigen is a surface marker on red blood cells Individuals who are AnWj-negative can have transfusion reactions if they receive AnWj-positive blood. Deletion of MAL antigen or weakening of MAL antigen as in lymphoid malignancy and Autoimmune Hemolytic Anemia can lead to AnWj antigen negative status. This is a common cause of…
