Circular RNAs (circRNAs) are closed circularized nucleic acids that differ from regular protein-coding messenger RNA molecules by maturation process and cellular functions. This article discusses how altered cellular levels of circRNAs lead to pathological changes in the cardiovascular system. CircRNAs were initially considered as waste cellular products of no apparent involvement. However, recent discoveries suggest that circRNAs can be involved in protein synthesis and be involved in multiple physiological processes including the development of heart.
Significant alteration of the concentrations of these RNAs can lead to the onset or progress of diseases including pathological conditions of the cardiovascular system. CircRNA in Myocardial Infarction Cardiovascular diseases (CVD) are the leading cause of mortalities in human. Myocardial infarction (MI) is responsible for the highest…
