T ourette syndrome is a developmental neuropsychiatric disorder defined by the combination of persistent brief, repetitive, nonrhythmic motor movements and vocalizations. As compared with other neurological syndromes of similar prevalence, research on Tourette syndrome has been relatively uncertain. Tourette's syndrome is a disease which has its onset during childhood and/or adolescence and is often life-long. The prevalence of this syndrome is estimated to be between one and ten per 1000.
The affected individuals are at increased risk of various comorbid neurobehavioral problems. Despite a longstanding interest in the neurobiology and genetics of the disorder, knowledge regarding specific cellular and molecular mechanisms of this disease has remained limited. Aetiology Genetic factors Genetic studies in twins and families provide compelling evidence that genetic factors, particularly.…
