A 57-year-old woman was presented with a history of triple negative breast cancer (TNBC). She reported left mastectomy 4 years ago. Received adjuvant dose-dense doxorubicin/cyclophosphamide (AC) plus weekly paclitaxel chemotherapy, but did not undergo postmastectomy radiation therapy. One year ago, she noticed increasing shortness of breath and cough. Found to have a pleural effusion and cutaneous nodules on left chest wall. Biopsy results confirmed recurrent TNBC.
She underwent therapeutic thoracentesis and commenced carboplatin AUC = 6 plus docetaxel 75 mg/m 2 x 7 cycles. After 5 months on treatment, progression on chest wall noted and Grade 1 neuropathy was found. Began oral capecitabine 1250 mg/m 2 twice daily. Progression after three cycles and neuropathy resolved.
