The US FDA has approved a copper intrauterine system (IUS) for the prevention of pregnancy in females of reproductive potential for up to three years. It is a next-generation, hormone-free, low-dose copper intrauterine device (IUD). Clinical evidence In clinical trials, the copper intrauterine system was evaluated for contraceptive efficacy over three years in 1,397 women aged 17-45. The IUS demonstrated a Pearl Index of 0.94 after one year and a cumulative three-year Pearl Index of 1.05, indicating 99% efficacy.
In separate clinical trials evaluating its safety (n = 1,904), the IUS achieved a 98.8% placement success rate. Dosage and administration Insert a single copper intrauterine system at the fundus of the uterine cavity. It must be removed or replaced after three years Contraindications Pregnancy or suspicion of pregnancy Uterine anomaly that distorts the uterine cavity and would…
