The optimal serum 25(OH)D level in pregnancy is unknown but should be at least 20 ng/mL (50 nmol/L). For routine supplementation, 2010 Institute of Medicine (IOM) report suggesting a recommended daily allowance of 600 international units vitamin D for all reproductive-age women, including during pregnancy and lactation.In a 2011 American College of Obstetricians and Gynecologists (ACOG) Committee Opinion, ACOG recommended routine supplementation with the dose in a standard prenatal vitamin until more evidence is available to support a different dose.Most prenatal vitamins contain 400 international units of vitamin D (cholecalciferol, ergocalciferol, or a mixture), but some preparations contain as little as 200 or as much as 1000 to 1200 international units per serving.
In pregnant women with vitamin D deficiency, the safety of 50,000 international units of vitamin D weekly for six to…
