Vitiligo is a relatively common acquired disorder of pigmentation characterized by the development of well-defined white macules on the skin. However, little is known about specific risk factors for disease development. The current article outlines a scientific evidence that linked the condition with tanning ability and blistering sunburn in women. Pathogenesis Biopsies of lesioned skin reveal a loss of epidermal melanocytes. Lesions may occur in a localized or generalized distribution and may coalesce into large, depigmented areas.
Given the contrast between the white areas and normal skin, the disease is most disfiguring in darker skin types and has a profound impact on the quality of life of both children and adults. Patients with vitiligo often experience stigmatization, social isolation, and low self-esteem. Etiology The etiology of vitiligo is unknown. Patients commonly attribute…
