The interplay of calcium, vit.D and magnesium in human nutrition calcium: calcium is the most abundant major mineral in the body. About 99% of the body’s calcium is stored in bones and the body uses the bones as a reservoir for and a source of calcium to maintain calcium homeostasis. Body is constantly regenerating its bone tissue. So it’s important to consume an adequate amount of this mineral daily. The ionized pool of calcium (about 1 %) in the circulatory system, extracellular fluid and various tissues mediates blood vessel contraction and dilation, muscle function, blood clotting, nerve transmission and hormonal secretion.

Blood calcium is tightly regulated and maintained at around 10 mg/dl. Calcium homeostasis is maintained by hormones that regulate calcium transport in the gut, kidneys and bone. Three primary hormones viz. parathyroid hormone (PTH), 1,25-dihydroxyvitamin D-3…